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It is often utilized to evaluate the warhead activity of covalent inhibitors due to its cysteine content and thiol structure
Additionally, the clinical irrelevance of sKlotho in AAC was demonstrated in this study in a multivariate regression analysis (Krishnasamy et al., 2017)
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100% achieved 5% or more, 93% achieved 10% or more, and 83% achieved 15% or more in Phase 2